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Cardiac resynchronization therapy : when and for whom? / R. G. Charles

By: Series: European Heart Journal Supplements. 4 : Supplement D, pages D117-D121 Publication details: April 2002Content type:
  • text
Media type:
  • unmediated
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  • volume
Subject(s): Summary: Potential candidates for cardiac resynchronization therapy (CRT) include patients with symptomatic congestive heart failure despite optimal medical therapy, who also have evidence of ventricular dyssynchrony, particularly left bundle branch block, with QRS duration in excess of 150 ms. Dyssynchrony may additionally be identified by echo-Doppler examination and tagged magnetic resonance imaging. Improved exercise capacity and quality of life, reduced sympathetic activation and fewer ventricular tachyarrhythmias are potential benefits of CRT. Ongoing trial results will be required to refine patient selection criteria and to demonstrate the possibility for prognostic as well as symptomatic benefit.
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Potential candidates for cardiac resynchronization therapy (CRT) include patients with symptomatic congestive heart failure despite optimal medical therapy, who also have evidence of ventricular dyssynchrony, particularly left bundle branch block, with QRS duration in excess of 150 ms. Dyssynchrony may additionally be identified by echo-Doppler examination and tagged magnetic resonance imaging. Improved exercise capacity and quality of life, reduced sympathetic activation and fewer ventricular tachyarrhythmias are potential benefits of CRT. Ongoing trial results will be required to refine patient selection criteria and to demonstrate the possibility for prognostic as well as symptomatic benefit.

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