Do proton pump inhibitors cause dementia? / William Simonson

A great deal of media attention has been given to a recently-published study that concluded that the prevalence of dementia was significantly greater in patients who had been regularly taking a proton pump inhibitor (PPI) including omeprazole (Prilosec), esomeprazole (Nexium), lansoprazole (Prevacid), pantoprazole (Protonix) or rabeprazole (Aciphex). The article was reported by many media outlets in stories with titles ranging from "Can Common Heartburn Drugs Raise Risk for Dementia?" and "Proton Pump Inhibitors Linked to Dementia" the former being a title that perhaps distorts the actual study findings misleading the reader to believe that a clear link exists between PPIs and dementia.

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