Associations between iron status and insulin resistance in Chinese children and adolescents : (Record no. 81734)

MARC details
000 -LEADER
fixed length control field 02512nam a2200253Ia 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 200930s2019 xx 000 0 und d
040 ## - CATALOGING SOURCE
Transcribing agency
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Wei, Junxiang.
245 #0 - TITLE STATEMENT
Title Associations between iron status and insulin resistance in Chinese children and adolescents :
Remainder of title findings from the China Health and Nutrition Survey /
Statement of responsibility, etc. Junxiang Wei, Xiaoqin Luo, Sirui Zhou, Xin He, Jinge Zheng, Xiaomin Sun, Wei Cui
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Date of publication, distribution, etc. 2019
336 ## - CONTENT TYPE
Content type term text
337 ## - MEDIA TYPE
Media type term unmediated
338 ## - CARRIER TYPE
Carrier type term volume
440 ## - SERIES STATEMENT/ADDED ENTRY--TITLE
Number of part/section of a work 28 : 4, page 819-825
Title Asia Pacific Journal of Clinical Nutrition
520 ## - SUMMARY, ETC.
Summary, etc. Background and Objectives: Iron homeostasis abnormalities are associated with insulin resistance (IR), but studies on such associations in children and adolescents are limited and have contrasting results. The purpose of this study was to determine the associations between indicators of iron status and IR, and assess if there are sex disparities in these associations. Methods and Study Design: We selected data of 689 children and adolescents (367 boys and 322 girls) aged 6-18 years in the analysis. Serum ferritin, transferrin, and soluble transferrin receptor (sTfR) levels were determined. The level of glycated hemoglobin (HbA1c) was assessed using high performance liquid chromatography. Homeostasis model assessment of insulin resistance (HOMA-IR) was used to indicate the status of insulin resistance. Stepwise and multivariate logistic regression analyses were computed to evaluate associations between iron status and glucose parameters. Results: The prevalence of IR (HOMAIR >3.16) and high HbA1c (HbA1c ≥5.7%) were 29.8% and 16.4%, respectively. Serum transferrin and sTfR were significant associated with HbA1c (p<0.001), while serum transferrin was associated with HOMA-IR (p<0.001). Furthermore, the highest transferring concentrations were associated with higher risks of both HOMAIR and high HbA1c, while decreased sTfR concentrations were associated with a risk of higher HbA1c in both children and adolescents. Conclusions: Serum transferrin and sTfR were statistically significantly associated with glucose parameters, which may suggest that transferrin and sTfR levels should be taken into consideration when studying IR in both boys and girls.
521 ## - TARGET AUDIENCE NOTE
Target audience note Nutrition.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Adolescents.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Children.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element HbA1c.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Insulin resistance.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Iron status.
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Articles
998 ## - LOCAL CONTROL INFORMATION (RLIN)
Cataloger's initials, CIN (RLIN) 85336
First Date, FD (RLIN) 143699
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Date last seen Price effective from Koha item type
    Library of Congress Classification     Manila Tytana Colleges Library Manila Tytana Colleges Library REFERENCE SECTION 09/30/2020   09/30/2020 09/30/2020 Articles
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