TY - BOOK AU - Butler,John Marshall TI - Forensic DNA typing: biology, technology, and genetics of STR markers SN - 9780121479527 PY - 2005/// CY - Burlington, MA PB - Elsevier/Academic Press KW - DNA fingerprinting KW - DNA KW - Synthesis KW - Forensic genetics KW - DNA Fingerprinting KW - Forensic Medicine KW - Genetic Markers N1 - Includes bibliographical references and indexes; Overview and history of DNA typing --; DNA biology review --; Sample collection, DNA extraction and DNA quantitation --; The polymerase chain reaction (DNA amplification) --; Commonly used short tandem repeat markers and commercial kits --; Biology of STRs : stutter products, non-template addition, microvariants, null alleles, and mutation rates --; Forensic issues : degraded DNA, PCR inhibition, contamination, mixed samples and low copy number --; Single nucleotide polymorphisms and other bi-allelic markers -- Y chromosome DNA testing -- Mitochondrial DNA analysis -- Non-human DNA testing and microbial forensics --; DNA separation methods : slab-gel and capillary electrophoresis --; DNA detection methods : fluorescent dyes and silver-staining --; Instrumentation for STR typing : ABI 310, ABI 3100, FMBIO systems --; STR genotyping issues --; Laboratory validation --; New technologies, automation, and expert systems --; Combined DNA index system (CODIS) and the use of DNA databases --; Basic genetic principles, statistics, and probability -- STR population database analyses -- Profile frequency estimates, likelihood ratios, and source attribution -- Approaches to statistical analysis of mixtures and degraded DNA -- Kinship and parentage testing -- Mass disaster DNA victim identification ER -